產(chǎn)品屬性

3D）

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• 產(chǎn)品描述 Beta-actin (human gene and protein abbreviation ACTB/ACTB) is one of six different actin isoforms which have been identified in humans. This is one of the two nonmuscle cytoskeletal actins. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus. Beta-actin has been shown to interact with SPTBN2. In addition, RNA-binding protein Sam68 was found to interact with the mRNA encoding β-actin, which regulates the synaptic formation of the dendritic spines with its cytoskeletal components. Beta-actin has been shown to activate eNOS, thereby increasing NO production. An eight-amino acid residue (326-333) in actin has been shown to mediate the interaction between actin and eNOS. Recurrent mutations in this gene have been associated to cases of diffuse large B-cell lymphoma. Beta actin is often used in Western blotting as a loading control, to normalize total protein amounts and check for eventual protein degradation in the samples. Its transcript is also commonly used as a housekeeping gene standard in qPCR. Its molecular weight is approximately 42 kDa.

• 產(chǎn)品名稱 Anti-Beta actin Mouse Monoclonal Antibody [B4-B2]

• 分子量 Predicted band size: 42 kDa

• 種屬反應(yīng)性 Human,Mouse,Rat

• 驗(yàn)證應(yīng)用 WB,IF-Cell,IHC-P,FC

• 抗體類型 小鼠單抗

• 免疫原 Synthetic peptide within N-terminal of Human beta actin.

• 偶聯(lián) Non-conjugated

• 性能

• 形態(tài) Liquid

• 濃度 2 mg/mL.

• 存放說明 Store at -20℃. Stable for 12 months from date of receipt.

• 存儲緩沖液 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

• 亞型 IgG1

• 純化方式 Immunogen affinity purified.

• 亞細(xì)胞定位 Cytoplasm.

• 數(shù)據(jù)鏈接 SwissProt: P60709 Human
  SwissProt: P60710 Mouse
  SwissProt: P60711 Rat
  

• 其它名稱

• A26C1A antibody

• A26C1B antibody

• ACTB antibody